The Holy of Holies is the center of this world.
In the Holy of Holies lies the foundation stone, from which the universe was founded.
According to the Midrash, this site is the source of the dust from which Adam was formed.
This site may be likened to the world’s “umbilical cord” – the point of connection to the Creator, the foundation and basis for all that was created in the wake of this single point.
The Holy of Holies marks the central point of contact, which is ringed by the Temple Mount, the entire city, and finally all of the Land of Israel – all concentrated around the single point, around the place where the heavenly world and the earthly world touch.
–Rabbi Adin Steinsaltz